Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.52 |
| ▸ | RARB | P10826 | 12/20 | 0.52 |
| ▸ | RARA | P10276 | 10/20 | 0.52 |
| ▸ | RXRA | P19793 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846968 | 0.87 | RARG (0.55) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL5846075 | 0.84 | RARB (0.60) | RARGRARBRARARXRARAB9A | |
| SCHEMBL5846597 | 0.84 | RARG (0.62) | RARGRARBRARARXRA | |
| SCHEMBL5699634 | 0.83 | RARG (0.52) | RARGRARBRARARXRACA12 | |
| SCHEMBL6730351 | 0.82 | RARB (0.53) | RARGRARBRARARXRAPDK2 | |
| SCHEMBL5845556 | 0.82 | RARG (0.57) | RARGRARBRARARXRAMEN1 | |
| SCHEMBL7566777 | 0.81 | RARB (0.57) | RARGRARBRARARXRAMEN1 | |
| SCHEMBL5845951 | 0.81 | RARG (0.56) | RARGRARBRARARXRACA12 | |
| SCHEMBL3303798 | 0.80 | CA12 (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5847708 | 0.80 | PDK2 (0.49) | RARGRARBRARARXRARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148245-B2 | Biphenyl derivatives substituted with an aromatic or heteroaromatic radical, and pharmaceutical and cosmetic compositions containing them | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-12-12 | — | — | US | disclosed |