Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 1.00 |
| ▸ | CXCR1 | P25024 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660018 | 0.88 | CXCR2 (0.79) | CXCR2CXCR1 | |
| SCHEMBL6850672 | 0.83 | CXCR2 (0.84) | CXCR2CXCR1MAPT | |
| SCHEMBL5846981 | 0.82 | CXCR1 (1.00) | CXCR2CXCR1 | |
| SCHEMBL5846271 | 0.81 | CXCR2 (1.00) | CXCR2CXCR1MAPT | |
| SCHEMBL5845444 | 0.81 | CXCR2 (1.00) | CXCR2CXCR1MAPT | |
| SCHEMBL6929735 | 0.79 | CXCR2 (0.81) | CXCR2CXCR1 | |
| SCHEMBL5845286 | 0.78 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL5845566 | 0.78 | CXCR2 (0.81) | CXCR2CXCR1 | |
| SCHEMBL5846794 | 0.77 | CXCR2 (0.80) | CXCR2CXCR1 | |
| SCHEMBL5845414 | 0.76 | CXCR2 (0.78) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7151112-B1 | Pharmaceutical uses and synthesis of nicotinamides | UCB SA (GB) | 2006-12-19 | — | — | US | disclosed |