⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305155 | 0.85 | CHRM2 (0.41) | — | |
| SCHEMBL17142328 | 0.83 | CHRM2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL28913389 | 0.81 | CHRM2 (0.44) | — | |
| SCHEMBL2498680 | 0.79 | CHRM2 (0.46) | — | |
| SCHEMBL3744068 | 0.79 | CHRM2 (0.46) | — | |
| SCHEMBL7499029 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL29220641 | 0.78 | CHRM2 (0.45) | — | |
| SCHEMBL25084544 | 0.76 | CHRM2 (0.39) | — | |
| SCHEMBL28129853 | 0.74 | CHRM2 (0.53) | — | |
| SCHEMBL27641293 | 0.74 | CHRM2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142635-A | Heterocyclic compounds useful in treatment of disease | EPIGEN BIOSCIENCES INC | 2015-12-09 | — | — | CN | disclosed |
| CN-101184769-A | Diagnostic and therapeutic agents | KARYON CTT LTD (FI) | 2008-05-21 | — | — | CN | disclosed |
| US-7132539-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-20060247224-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | disclosed |
| CN-1227248-C | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | AVENTIS PHARMA GMBH (DE) | 2005-11-16 | — | — | CN | disclosed |
| CN-1221535-C | Spiroimidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMA GMBH (DE) | 2005-10-05 | — | — | CN | disclosed |
| EP-1556361-A2 | 2-ALKYL-(2-AMINO-3-ARYL-PROPIONYL)-PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY | THE PROCTER & GAMBLE COMPANY (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20050010031-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | disclosed |
| CN-1496360-A | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | ������ҽҩ�¹�����˾ | 2004-05-12 | — | — | CN | disclosed |
| WO-2004037797-A2 | 2 - ALKYL - (2 - AMINO - 3 - ARYL - PROPIONYL) - PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY | THE PROCTER & GAMBLE COMPANY (US) | 2004-05-06 | — | — | WO | disclosed |
| US-6498161-B1 | TREATING INFECTION BY HIV; DELAYING OF THE ONSET OF AIDS; ASTHMA, ALLERGIC RHINITIS, DERMATITIS, CONJUNCTIVITIS, ATHEROSCLEROSIS OR RHEUMATOID ARTHRITIS | MERCK & CO., INC. | 2002-12-24 | — | — | US | disclosed |
| CN-1356986-A | Spiroimidazolidine derivatives, their prepn. their use and pharmaceutical prepns. comprising them | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | CN | disclosed |
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1171122-A4 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1171122-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |
| WO-2000059498-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000059502-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| WO-2000059497-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |