Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861119 | 1.00 | MEN1 (0.40) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6860915 | 1.00 | MEN1 (0.40) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6860903 | 0.89 | PDK2 (0.34) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6860685 | 0.89 | PDK2 (0.33) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL5847178 | 0.86 | PDK2 (0.46) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL5846572 | 0.84 | PDK2 (0.47) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6854461 | 0.83 | MEN1 (0.42) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6861430 | 0.81 | PDK2 (0.46) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6863559 | 0.79 | PDK2 (0.47) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL6863550 | 0.78 | PDK2 (0.46) | MEN1APAF1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187224-B1 | ORGANIC SPIRO COMPOUNDS WHICH COMPRISE A CONJUGATED SYSTEM | AXIVA GMBH (DE) | 2001-02-13 | — | — | US | claimed |
| US-7088757-B1 | Use of spiro compounds as laser dyes | SEMICONDUCTORS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| EP-0935691-B1 | OPTICAL BRIGHTENING AGENT | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-0947006-B1 | RADIATION DETECTOR | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-0850492-B1 | PHOTO-VOLTAIC CELL WITH A SPIRO-COMPOUND | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-03-12 | — | — | EP | disclosed |
| US-6504042-B1 | Optic couplers, radiation measuring instruments, prisms and waveguides comprising armophous spirobi-9-silafluorenes or spirobifluorenes having solubility and stability | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-01-07 | — | — | US | disclosed |
| EP-0676461-B1 | Spiro compounds and their application as electroluminescence materials | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-1053578-B1 | USE OF SPIRO COMPOUNDS AS LASER DYES | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-05-08 | — | — | EP | disclosed |
| US-6187224-B1 | ORGANIC SPIRO COMPOUNDS WHICH COMPRISE A CONJUGATED SYSTEM | AXIVA GMBH (DE) | 2001-02-13 | — | — | US | disclosed |
| US-5885368-A | Photovoltaic cell | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5840217-A | LIGHT-EMITTING, CHARGE-TRANSPORT, CHARGE-INJECTION MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0768563-A1 | Use of spiro compounds as active materials for non-linear optic | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0676461-A2 | Spiro compounds and their application as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |