Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529189 | 1.00 | CYP4F2 (0.45) | CYP4F2CYP4A11POLBAPEX1RECQL | |
| Hydrochloric Acid SCHEMBL5847338 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11POLBAPEX1RECQL | |
| Hydrochloric Acid SCHEMBL6529187 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11POLBAPEX1RECQL | |
| Hydrochloric Acid SCHEMBL5847334 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11POLBAPEX1RECQL | |
| SCHEMBL5847508 | 0.87 | CYP4F2 (0.61) | CYP4F2CYP4A11LOXL2ITGB3ITGA2B | |
| SCHEMBL6529352 | 0.87 | CYP4F2 (0.61) | CYP4F2CYP4A11LOXL2ITGB3ITGA2B | |
| SCHEMBL12963751 | 0.86 | CYP4F2 (0.45) | CYP4F2CYP4A11POLBAPEX1RECQL | |
| Hydrochloric Acid SCHEMBL5847504 | 0.86 | CYP4F2 (0.60) | CYP4F2CYP4A11LOXL2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6529351 | 0.86 | CYP4F2 (0.60) | CYP4F2CYP4A11LOXL2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL5847506 | 0.86 | CYP4F2 (0.60) | CYP4F2CYP4A11LOXL2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034051-B2 | Fused bicyclic carboxamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2006-04-25 | — | — | US | disclosed |
| US-20050054630-A1 | Fused bicyclic carboxamide derivatives and methods of their use | CUBIST PHARMACEUTICALS, INC. | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054630-A1 | Fused bicyclic carboxamide derivatives and methods of their use | PAICS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CPS1 | CYP4F2 367/4885CYP4A11 742/4885POLB 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.