⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355931 | 1.00 | — | — | |
| SCHEMBL631310 | 0.86 | — | — | |
| SCHEMBL59981 | 0.81 | — | — | |
| SCHEMBL3895632 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL104576 | 0.78 | — | — | |
| SCHEMBL7779245 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL149818 | 0.78 | — | — | |
| SCHEMBL3886927 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL28154755 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL28153705 | 0.77 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3529 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016037223-A1 | DIRHODIUM COMPOUNDS AND METHODS OF USE | GHANEM ASHRAF (AU) | 2016-03-17 | — | — | WO | claimed |
| US-20130087745-A1 | SOLUBLE PRECURSORS AND SOLUTION-BASED PROCESSES FOR PHOTOVOLTAICS | PRECURSOR ENERGETICS, INC. (US) | 2013-04-11 | — | — | US | claimed |
| WO-2006065842-A2 | 5,6,7,8-TETRAHYDROQUINOLINES AND RELATED COMPOUNDS AND USES THEREOF | SYNTA PHARMACEUTICALS CORP. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1663227-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | Synta Pharmaceuticals Corporation (US) | 2006-06-07 | — | — | EP | claimed |
| US-20050203119-A1 | Dihydropyridine compounds for treating or preventing metabolic disorders | SYNTA PHARMACEUTICAL CORP. | 2005-09-15 | — | — | US | claimed |
| WO-2005025507-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | SYNTA PHAMACEUTICALS CORP. (US) | 2005-03-24 | — | — | WO | claimed |
| EP-0242801-B1 | HYDROCARBYLOXY MAGNESIUM HALIDES | LITHIUM CORPORATION OF AMERICA (US) | 1993-03-10 | — | — | EP | claimed |
| US-4792640-A | REACTING ACTIVATED MAGNESIUM METAL WITH ALKYL HALIDE, REACTING PRODUCT WITH ALCOHOL | LITHIUM CORPORATION OF AMERICA (US) | 1988-12-20 | — | — | US | claimed |
| EP-0242801-A2 | Hydrocarbyloxy magnesium halides | LITHIUM CORPORATION OF AMERICA (US) | 1987-10-28 | — | — | EP | claimed |
| WO-2024148932-A1 | EGFR C797S MUTATION INHIBITOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-118344364-A | Amino-substituted fused heteroaryl compounds, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344365-A | Condensed heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113939516-B | Methods and compositions for targeting protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114845739-B | Pharmaceutical conjugate of eribulin derivative, preparation method and application thereof in medicine | 上海森辉医药有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
| EP-0737660-A1 | Inhibition of unsaturated monomers with 7-aryl quinone methides | CIBA-GEIGY AG (CH) | 1996-10-16 | — | — | EP | disclosed |
| EP-0737659-A1 | 7-Substituted quinone methides as inhibitors for unsaturated monomers | CIBA-GEIGY AG (CH) | 1996-10-16 | — | — | EP | disclosed |
| US-4804654-A | INSECTICIDES, MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| CN-86107067-A | Weedicide | — | 1987-10-21 | — | — | CN | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |