Lithium

Lithium

SCHEMBL585057

Cc1ccc(COCc2ccc(C)cc2)cc1.[Li]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.61
KCNH2 Q12809 2/20 0.61
TSHR P16473 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
IDO1 P14902 1/20 0.48
ACHE P22303 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
MAOB P27338 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
PARP10 Q53GL7 1/20 0.41
CASP3 P42574 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3161372 0.97 AGXT (0.64) AGXTKCNH2TSHRCA1CA2
SCHEMBL9617939 0.97 AGXT (0.64) AGXTKCNH2TSHRCA1CA2
Potassium SCHEMBL586332 0.94 AGXT (0.61) AGXTKCNH2TSHRCA1CA2
SCHEMBL586154 0.94 AGXT (0.61) AGXTKCNH2TSHRCA1CA2
SCHEMBL257896 0.87 TSHR (0.71) AGXTKCNH2TSHRCA1CA2
SCHEMBL9861794 0.86 AGXT (0.58) AGXTKCNH2TSHRCA1CA2
SCHEMBL12270447 0.86 AGXT (0.58) AGXTKCNH2TSHRCA1CA2
SCHEMBL257780 0.84 AGXT (0.56) AGXTKCNH2TSHRCA1CA2
P-Xylene SCHEMBL19206957 0.84 TSHR (0.75) AGXTKCNH2TSHRCA1CA2
SCHEMBL12677695 0.84 KCNH2 (0.52) AGXTKCNH2TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119749-B2 Method of taking (meth)acrylic ester polymer out of liquid reaction mixture KURARAY CO., LTD. (JP) 2012-02-21 US disclosed
EP-1916262-B1 METHOD OF TAKING (METH)ACRYLIC ESTER POLYMER OUT OF LIQUID REACTION MIXTURE KURARAY CO (JP) 2012-02-15 EP disclosed
US-7973117-B2 Milder temperatures, higher speed; controlled molecular weight and narrow distribution thermoplastic elastomers KURARAY CO., LTD. (JP) 2011-07-05 US disclosed
US-20090118450-A1 METHOD OF TAKING (METH)ACRYLIC ESTER POLYMER OUT OF LIQUID REACTION MIXTURE KURARAY CO., LTD. (JP) 2009-05-07 US disclosed
EP-1780222-B1 PROCESS FOR CONTINUOUSLY PRODUCING (METH)ACRYLIC ESTER POLYMER OR COPOLYMER KURARAY CO (JP) 2008-11-26 EP disclosed
US-20080139759-A1 Process For Continuously Producing (Meth)Acrylic Ester Polymer or Copolymer KURARAY CO., LTD. (JP) 2008-06-12 US disclosed
EP-1916262-A1 METHOD OF TAKING (METH)ACRYLIC ESTER POLYMER OUT OF LIQUID REACTION MIXTURE Kuraray Co., Ltd. (JP) 2008-04-30 EP disclosed
EP-1780222-A1 PROCESS FOR CONTINUOUSLY PRODUCING (METH)ACRYLIC ESTER POLYMER OR COPOLYMER KURARAY CO., LTD. (JP) 2007-05-02 EP disclosed