Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431914 | 1.00 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL23506579 | 1.00 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL6432105 | 1.00 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL6439332 | 1.00 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL184537 | 1.00 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL6436067 | 0.98 | SMN1; SMN2 (0.62) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| Methacrylic Acid SCHEMBL28458538 | 0.94 | NPC1 (0.59) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL22677485 | 0.93 | SMN1; SMN2 (0.56) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL368410 | 0.89 | — | — | |
| SCHEMBL730569 | 0.85 | SMN1; SMN2 (0.46) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832613-B9 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | KANEKA CORP (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-1832613-B1 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | KANEKA CORP (JP) | 2012-02-15 | — | — | EP | disclosed |
| CN-101090919-B | Graft copolymer, method for producing same and resin composition containing such graft copolymer | KANEGAFUCHI CHEMICAL IND | 2010-12-01 | — | — | CN | disclosed |
| US-20080085975-A1 | Graft Copolymer, Method For Producing The Same And Resin Composition Containing The Graft Copolymer | KANEKA CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| CN-101090919-A | Graft copolymer, method for producing same and resin composition containing such graft copolymer | KANEGAFUCHI CHEMICAL IND (JP) | 2007-12-19 | — | — | CN | disclosed |
| EP-1832613-A1 | GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER | Kaneka Corporation (JP) | 2007-09-12 | — | — | EP | disclosed |