Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.59 |
| ▸ | PPARG | P37231 | 9/20 | 0.59 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852080 | 0.91 | PPARD (0.50) | PPARDPPARGPPARAPTPN1CYP2C9 | |
| SCHEMBL5220549 | 0.85 | PPARD (0.58) | PPARDPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL5215033 | 0.85 | PPARD (0.58) | PPARDPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL5215031 | 0.85 | PPARD (0.58) | PPARDPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL5850595 | 0.81 | PPARG (0.51) | PPARDPPARGPPARAPTPN1CYP2C9 | |
| SCHEMBL5219166 | 0.80 | PPARD (0.54) | PPARDPPARGPPARAPTPN1 | |
| SCHEMBL14432285 | 0.80 | PPARD (0.54) | PPARDPPARGPPARAPTPN1 | |
| SCHEMBL5219010 | 0.79 | PPARD (0.57) | PPARDPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL5218331 | 0.79 | PPARD (0.57) | PPARDPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL5218325 | 0.79 | PPARD (0.57) | PPARDPPARGPPARAPTPN1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153878-B2 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1480640-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |