Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850439 | 0.86 | LPAR3 (0.42) | LPAR3LPAR2CA2CA9 | |
| SCHEMBL9306349 | 0.77 | LPAR3 (0.84) | LPAR3LPAR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL5850821 | 0.77 | LPAR3 (0.64) | LPAR3LPAR2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL9492549 | 0.76 | LPAR3 (0.81) | LPAR3LPAR2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL16581542 | 0.74 | LPAR3 (0.67) | LPAR3LPAR2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL11322955 | 0.73 | LPAR3 (0.70) | LPAR3LPAR2ALDH1A1TSHRLMNA | |
| SCHEMBL20065637 | 0.73 | LPAR3 (0.70) | LPAR3LPAR2ALDH1A1TSHRLMNA | |
| SCHEMBL17975103 | 0.73 | LPAR3 (0.70) | LPAR3LPAR2ALDH1A1TSHRLMNA | |
| SCHEMBL10425343 | 0.72 | LPAR3 (0.44) | LPAR3LPAR2TSHRLMNACYP3A4 | |
| SCHEMBL31742531 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |