Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511370 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL1101448 | 0.86 | CYP2C19 (0.72) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL2150400 | 0.86 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL3755582 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL9485955 | 0.85 | SRC (0.48) | SMN1; SMN2CYP2C19BLMSRCKMT2A | |
| SCHEMBL27375427 | 0.84 | CYP2C19 (0.70) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| Hydrochloric Acid SCHEMBL28980283 | 0.84 | CYP2C19 (0.70) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL24763321 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL1413702 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP2C19BLMSRCPOLB | |
| SCHEMBL11510266 | 0.79 | CYP2C19 (0.54) | SMN1; SMN2CYP2C19SRCPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |