Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
| ▸ | MVD | P53602 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585600 | 0.86 | LPAR3 (0.48) | LPAR3LPAR2LPAR1 | |
| SCHEMBL4414178 | 0.80 | LPAR3 (0.52) | LPAR3LPAR2LPAR1 | |
| SCHEMBL11712457 | 0.77 | LPAR3 (0.34) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL5085588 | 0.74 | CYP3A4 (0.46) | LPAR3LPAR2LPAR1TSHRCYP3A4 | |
| SCHEMBL13859977 | 0.74 | MVD (0.33) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL5850574 | 0.73 | LPAR3 (0.38) | LPAR3LPAR2LPAR1TSHRITPR3 | |
| SCHEMBL672799 | 0.71 | CYP3A4 (0.61) | LPAR3LPAR2LPAR1TSHRCYP3A4 | |
| SCHEMBL8211315 | 0.71 | LPAR3 (0.41) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL2414727 | 0.71 | LPAR3 (0.41) | LPAR3LPAR2LPAR1MVD | |
| SCHEMBL4393949 | 0.70 | LPAR3 (0.39) | LPAR3LPAR2LPAR1TSHRITPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |