Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.30 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089589 | 0.84 | KCNA3 (0.39) | KCNA3RARBALDH3A1HDAC3HDAC4 | |
| SCHEMBL3038199 | 0.82 | TDP1 (0.41) | KCNA3RARBSLC2A1L3MBTL1GAA | |
| SCHEMBL3016040 | 0.81 | KCNA3 (0.36) | KCNA3RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL8941219 | 0.77 | TDP1 (0.41) | KCNA3SLC2A1PRSS1GAATDP1 | |
| SCHEMBL919130 | 0.77 | KCNA3 (0.46) | KCNA3ALDH3A1HDAC3HDAC4HDAC1 | |
| SCHEMBL10608344 | 0.76 | RARB (0.50) | KCNA3RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL921280 | 0.76 | KCNA3 (0.44) | KCNA3ALDH3A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9357916 | 0.75 | KCNA3 (0.38) | KCNA3RARBALDH3A1HDAC3HDAC4 | |
| SCHEMBL921941 | 0.75 | KCNA3 (0.44) | KCNA3ALDH3A1HDAC3HDAC4HDAC1 | |
| SCHEMBL919856 | 0.75 | KCNA3 (0.44) | KCNA3ALDH3A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074829-B2 | Antiestrogens, process for their production and their pharmaceutical use | SCHERING AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20030162830-A1 | New antiestrogens, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6559181-B1 | A method to treat endometrial carcinoma, prostate cancer, or prostate hyperplasia comprising administering to a patient in need of such treatment an effective dose of a 3,4-Diphenyl-bicyclo(4.3.0)nonyl compound of formula I | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| EP-1086077-A1 | NOVEL ANTIESTROGENS, A METHOD FOR THE PRODUCTION THEREOF, AND THEIR PHARMACEUTICAL APPLICATION | Schering Aktiengesellschaft (DE) | 2001-03-28 | — | — | EP | disclosed |
| US-6166075-A | Antiestrogens, process for their production and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| WO-1999064393-A1 | NOVEL ANTIESTROGENS, A METHOD FOR THE PRODUCTION THEREOF, AND THEIR PHARMACEUTICAL APPLICATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162830-A1 | New antiestrogens, process for their production and their pharmaceutical use | CYP19A1, NR5A1, HSD17B11 | KCNA3 2510/4885RARB 1135/4885ALDH3A1 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.