⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216364 | 0.76 | — | — | |
| SCHEMBL27944960 | 0.70 | — | — | |
| SCHEMBL17608785 | 0.67 | — | — | |
| SCHEMBL27752360 | 0.67 | — | — | |
| SCHEMBL19991234 | 0.67 | — | — | |
| SCHEMBL6286747 | 0.67 | — | — | |
| SCHEMBL5370315 | 0.67 | — | — | |
| SCHEMBL2458378 | 0.67 | — | — | |
| SCHEMBL31491251 | 0.62 | — | — | |
| SCHEMBL15520455 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108546246-A | A kind of preparation method of double pyridylcarbinols | 湖南华腾制药有限公司 | 2018-09-18 | — | — | CN | claimed |
| CN-110143911-B | Preparation method of N- (indole-N-formyl) -alpha-amino amide derivative | 浙江大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-110143911-A | A kind of preparation method of N- (indoles-N- formoxyl)-alpha-aminoamide derivatives | 浙江大学 | 2019-08-20 | — | — | CN | disclosed |
| US-20130225617-A1 | INDOLES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2013-08-29 | — | — | US | disclosed |
| US-8450243-B2 | Herbicidal quinoline and 1,8-naphthyridine compounds | SYNGENTA LIMITED (GB) | 2013-05-28 | — | — | US | disclosed |
| EP-2417132-B1 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | SYNGENTA LTD (GB) | 2013-04-17 | — | — | EP | disclosed |
| US-8394836-B2 | Indoles and their therapeutic use | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20120094833-A1 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | SYNGENTA CROP PROTECTION, LLC (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2012045721-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-04-12 | — | — | WO | disclosed |
| EP-2417132-A2 | HERBICIDAL QUINOLINE AND 1,8-NAPHTHYRIDINE COMPOUNDS | Syngenta Limited (GB) | 2012-02-15 | — | — | EP | disclosed |
| EP-2327693-A1 | Indoles and their therapeutic use | Pulmagen Therapeutics (Asthma) Limited (GB) | 2011-06-01 | — | — | EP | disclosed |
| US-20110071175-A1 | Indoles and Their Therapeutic Use | GB005, INC. | 2011-03-24 | — | — | US | disclosed |
| CN-101970405-A | Indoles and their therapeutic use | PULMAGEN THERAPEUTICS ASTHMA L | 2011-02-09 | — | — | CN | disclosed |
| WO-2010116122-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |
| EP-2229358-A1 | INDOLES AND THEIR THERAPEUTIC USE | Pulmagen Therapeutics (Asthma) Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077728-A1 | INDOLES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |
| US-5708180-A | CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |