Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 18/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | SCN1A | P35498 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.60 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.60 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.60 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855155 | 1.00 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL5855163 | 1.00 | CACNA1B (1.00) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL10719905 | 0.93 | CACNA1B (0.87) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL10719900 | 0.93 | CACNA1B (0.87) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL22746498 | 0.92 | CACNA1B (0.84) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL27014861 | 0.90 | CACNA1B (0.81) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL5854797 | 0.89 | CACNA1B (0.80) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL5854804 | 0.89 | CACNA1B (0.80) | CACNA1BADORA3CACNA1CKMT2AABCC4 | |
| SCHEMBL5855162 | 0.86 | CACNA1B (0.79) | CACNA1B | |
| SCHEMBL5855158 | 0.86 | CACNA1B (0.79) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995179-B2 | Dihydropyridine derivative | AJINOMOTO CO., INC. (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20020111494-A1 | Novel dihydropyridine derivative | AJINOMOTO CO., INC. (JP) | 2002-08-15 | — | — | US | disclosed |
| US-6350766-B1 | PAIN, CNS | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-0985667-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111494-A1 | Novel dihydropyridine derivative | CACNA1B, CACNA1D, CACNA1S | CACNA1B 1/4885ADORA3 1224/4885CACNA1C 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.