Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 16/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855267 | 1.00 | CACNA1B (0.57) | CACNA1BCYP2C9MEN1KMT2AKDM4E | |
| SCHEMBL5854633 | 0.89 | CACNA1B (0.72) | CACNA1BCYP2C9MEN1KMT2AKDM4E | |
| SCHEMBL5854638 | 0.89 | CACNA1B (0.72) | CACNA1BCYP2C9MEN1KMT2AKDM4E | |
| SCHEMBL5854745 | 0.88 | CACNA1B (0.61) | CACNA1BMEN1KMT2AKDM4ENR1I2 | |
| SCHEMBL5854742 | 0.88 | CACNA1B (0.61) | CACNA1BMEN1KMT2AKDM4ENR1I2 | |
| SCHEMBL5856236 | 0.86 | CACNA1B (0.76) | CACNA1BMEN1KMT2ANR1I2NR3C1 | |
| SCHEMBL5856241 | 0.86 | CACNA1B (0.76) | CACNA1BMEN1KMT2ANR1I2NR3C1 | |
| SCHEMBL5857977 | 0.85 | CACNA1B (0.66) | CACNA1BMEN1KMT2ANR1I2NR3C1 | |
| SCHEMBL5857973 | 0.85 | CACNA1B (0.66) | CACNA1BMEN1KMT2ANR1I2NR3C1 | |
| SCHEMBL820500 | 0.85 | CYP2C9 (0.74) | CYP2C9MEN1KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995179-B2 | Dihydropyridine derivative | AJINOMOTO CO., INC. (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20020111494-A1 | Novel dihydropyridine derivative | AJINOMOTO CO., INC. (JP) | 2002-08-15 | — | — | US | disclosed |
| US-6350766-B1 | PAIN, CNS | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-0985667-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111494-A1 | Novel dihydropyridine derivative | CACNA1B, CACNA1D, CACNA1S | CACNA1B 1/4885CYP2C9 4596/4885MEN1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.