SCHEMBL5855816

SCHEMBL5855816

C[Si](C)(C)O[Si](C)(C)C.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2343587 0.94
Iodide SCHEMBL31692685 0.89
SCHEMBL5596132 0.89
Bromide SCHEMBL28372223 0.89
Ammonia Solution, Strong SCHEMBL3401376 0.89
Potassium SCHEMBL504313 0.89
SCHEMBL1059751 0.89
SCHEMBL5596133 0.89
SCHEMBL5697311 0.89
SCHEMBL29287068 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078124-A1 METHODS OF PREPARING ERGOLINE ANALOGS UNIV CALIFORNIA (US) 2026-03-19 US claimed
WO-2025137231-A1 METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2025-06-26 WO claimed
WO-2024059495-A1 METHODS OF PREPARING ERGOLINE ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO claimed
CN-110317212-B Synthesis of polycyclic carbamoylpyridone compounds 吉利德科学公司 2022-10-21 CN claimed
EP-3527573-B9 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES INC (US) 2022-07-06 EP claimed
CN-114394983-A Synthesis of polycyclic carbamoylpyridone compounds 吉利德科学公司 2022-04-26 CN claimed
US-10975096-B2 Synthesis of polycyclic-carbamoylpyridone compounds GILEAD SCIENCES, INC. (US) 2021-04-13 US claimed
EP-3783001-A1 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS Gilead Sciences, Inc. (US) 2021-02-24 EP claimed
EP-3527573-B1 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES INC (US) 2020-08-12 EP claimed
US-20200223866-A1 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES, INC. 2020-07-16 US claimed
EP-2970348-A1 BIS(2-INDENYL) METALLOCENE COMPLEX Saudi Basic Industries Corporation (SA) 2016-01-20 EP claimed
US-20150368264-A1 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES, INC. 2015-12-24 US claimed
WO-2015195656-A2 SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS GILEAD SCIENCES ,INC. (US) 2015-12-23 WO claimed
CN-105073764-A Bis (2-indenyl) metallocene complexes SAUDI BASIC IND CORP 2015-11-18 CN claimed
WO-2014139949-A1 BIS(2-INDENYL) METALLOCENE COMPLEX SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-09-18 WO claimed
US-20140275455-A1 BIS(2-INDENYL) METALLOCENE COMPLEX SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-09-18 US claimed
CN-102026941-A Method for synthesizing ethynylcyclopropane LONZA AG 2011-04-20 CN claimed
CN-101056672-A Process for the preparation of { 3- [2 - [ (1R) -1- [3, 5-bis (trifluoromethyl) phenyl ] ethoxy ] -3 (S) - (4-fluorophenyl) morpholin-4-yl ] methyl ] -5-oxo-4, 5-dihydro- [1,2,4] -triazol-1-yl } phosphonic acid MERCK & CO INC (US) 2007-10-17 CN claimed
EP-0200307-B1 IMPROVED PROCESS FOR PRODUCTION OF QUINOLINE-3-CARBOXYLIC ACID ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 1989-12-20 EP claimed
EP-0200307-A1 Improved process for production of quinoline-3-carboxylic acid antibacterial agents WARNER-LAMBERT COMPANY (US) 1986-11-05 EP claimed