⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307575 | 0.97 | — | — | |
| SCHEMBL18631787 | 0.95 | — | — | |
| SCHEMBL1059754 | 0.95 | — | — | |
| SCHEMBL8761842 | 0.73 | — | — | |
| SCHEMBL21527925 | 0.71 | — | — | |
| SCHEMBL21679576 | 0.70 | — | — | |
| SCHEMBL8755728 | 0.70 | — | — | |
| SCHEMBL132533 | 0.69 | — | — | |
| SCHEMBL2527586 | 0.69 | — | — | |
| SCHEMBL21641959 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078124-A1 | METHODS OF PREPARING ERGOLINE ANALOGS | UNIV CALIFORNIA (US) | 2026-03-19 | — | — | US | claimed |
| WO-2025137231-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2025-06-26 | — | — | WO | claimed |
| WO-2024059495-A1 | METHODS OF PREPARING ERGOLINE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-21 | — | — | WO | claimed |
| CN-110317212-B | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-10-21 | — | — | CN | claimed |
| EP-3527573-B9 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2022-07-06 | — | — | EP | claimed |
| CN-114394983-A | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-04-26 | — | — | CN | claimed |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | GILEAD SCIENCES, INC. (US) | 2021-04-13 | — | — | US | claimed |
| EP-3783001-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2021-02-24 | — | — | EP | claimed |
| EP-3527573-B1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2020-08-12 | — | — | EP | claimed |
| US-20200223866-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES, INC. | 2020-07-16 | — | — | US | claimed |
| EP-3157933-A2 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2017-04-26 | — | — | EP | claimed |
| CN-103819475-B | Synthetic method of sitagliptin and salt thereof | 浙江新和成股份有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-102977142-B | The preparation method of fosaprepitant dimeglumine | 江苏豪森药业集团有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-106470975-A | Synthesis of Polycyclic Carbamoylpyridone Compounds | 吉利德科学公司 | 2017-03-01 | — | — | CN | claimed |
| US-20150368264-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-24 | — | — | US | claimed |
| WO-2015195656-A2 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES ,INC. (US) | 2015-12-23 | — | — | WO | claimed |
| CN-105073764-A | Bis (2-indenyl) metallocene complexes | SAUDI BASIC IND CORP | 2015-11-18 | — | — | CN | claimed |
| US-20140275455-A1 | BIS(2-INDENYL) METALLOCENE COMPLEX | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2014-09-18 | — | — | US | claimed |
| CN-102026941-A | Method for synthesizing ethynylcyclopropane | LONZA AG | 2011-04-20 | — | — | CN | claimed |
| CN-101056672-A | Process for the preparation of { 3- [2 - [ (1R) -1- [3, 5-bis (trifluoromethyl) phenyl ] ethoxy ] -3 (S) - (4-fluorophenyl) morpholin-4-yl ] methyl ] -5-oxo-4, 5-dihydro- [1,2,4] -triazol-1-yl } phosphonic acid | MERCK & CO INC (US) | 2007-10-17 | — | — | CN | claimed |