Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855951 | 0.90 | CYP19A1 (0.33) | HTR1AHTR2BSIGMAR1CYP19A1 | |
| SCHEMBL5857506 | 0.83 | BACE1 (0.38) | BACE1HTR1AHTR2BSIGMAR1CTSD | |
| SCHEMBL7588543 | 0.83 | PTPN1 (0.31) | — | |
| SCHEMBL7587357 | 0.83 | PTPN1 (0.31) | — | |
| SCHEMBL5855979 | 0.82 | ESR1 (0.38) | HTR1AHTR2BSIGMAR1 | |
| SCHEMBL5854301 | 0.81 | BACE1 (0.35) | BACE1HTR1AHTR2BSIGMAR1CTSD | |
| SCHEMBL5854227 | 0.80 | ESR1 (0.33) | HTR2BSIGMAR1 | |
| SCHEMBL5857401 | 0.79 | HTR2B (0.33) | HTR1AHTR2BSIGMAR1 | |
| SCHEMBL7585889 | 0.78 | ESR1 (0.36) | HTR2BSIGMAR1 | |
| SCHEMBL7588656 | 0.78 | ESR1 (0.36) | HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |