Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.67 |
| ▸ | CA1 | P00915 | 15/20 | 0.67 |
| ▸ | CA2 | P00918 | 15/20 | 0.67 |
| ▸ | CA4 | P22748 | 15/20 | 0.67 |
| ▸ | CA9 | Q16790 | 15/20 | 0.67 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5724718 | 0.99 | CA12 (0.66) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049391 | 0.89 | CA12 (0.70) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049385 | 0.88 | CA12 (0.69) | CA12CA1CA2CA4CA9 | |
| SCHEMBL4947759 | 0.84 | CA12 (0.75) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5726684 | 0.84 | CA12 (0.67) | CA12CA1CA2CA4CA9 | |
| SCHEMBL6059327 | 0.84 | CA12 (0.51) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL6058754 | 0.84 | CA12 (0.73) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5726193 | 0.83 | CA12 (0.66) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049386 | 0.81 | PTGER2 (0.62) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5725362 | 0.80 | CA12 (0.73) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998423-B2 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. (US) | 2006-02-14 | — | — | US | claimed |