Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586442 | 1.00 | NR1H2 (0.46) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL20061028 | 0.94 | KDM4E (0.49) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL20784540 | 0.87 | NR1H2 (0.46) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL25311379 | 0.85 | NR1H2 (0.46) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL25314249 | 0.85 | NR1H2 (0.46) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL364778 | 0.84 | NR1H2 (0.51) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL31662078 | 0.84 | NR1H2 (0.51) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL344474 | 0.84 | NR1H2 (0.51) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL6398279 | 0.84 | NR1H2 (0.51) | NR1H2KDM4EPKMHPGDALDH1A1 | |
| SCHEMBL25547496 | 0.83 | KDM4E (0.49) | NR1H2KDM4EPKMHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417124-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | Eli Lilly and Company (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117979-A2 | SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR | ELI LILLY AND COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |