Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.64 |
| ▸ | PPARA | Q07869 | 5/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860673 | 0.94 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL5861832 | 0.94 | PPARD (0.67) | PPARDPPARAPPARG | |
| SCHEMBL5860628 | 0.91 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL5862798 | 0.88 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL5861830 | 0.87 | PPARD (0.64) | PPARDPPARAPPARG | |
| SCHEMBL5862747 | 0.85 | PPARD (0.69) | PPARDPPARAPPARG | |
| SCHEMBL6162923 | 0.84 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL5860831 | 0.83 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL4810261 | 0.83 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL5862764 | 0.82 | PPARD (0.60) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091237-B2 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1392674-B1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | GLAXO GROUP LIMITED (GB) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.