Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586222 | 0.86 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL586223 | 0.86 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL602359 | 0.79 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL706710 | 0.78 | KCNH2 (1.00) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3860284 | 0.78 | KCNH2 (0.98) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4140150 | 0.78 | KCNH2 (0.98) | KCNH2 | |
| SCHEMBL13736100 | 0.78 | KCNH2 (0.75) | KCNH2 | |
| SCHEMBL1607074 | 0.76 | KCNH2 (0.67) | KCNH2 | |
| SCHEMBL15309951 | 0.73 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL603347 | 0.73 | KCNH2 (0.68) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417141-A1 | 2-HYDROXYETHYL-1H-QUINOLIN-2-ONE DERIVATIVES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | Actelion Pharmaceuticals Ltd. (CH) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116337-A1 | 2-HYDROXYETHYL-1H-QUINOLIN-2-ONE DERIVATIVES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ACTELION PHARMACEUTICALS LTD (CH) | 2010-10-14 | — | — | WO | disclosed |