Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373166 | 0.86 | HSP90AA1 (0.50) | HSP90AA1 | |
| SCHEMBL18327346 | 0.83 | CYP2A6 (0.44) | HSP90AA1CYP2A6CLK4ADRB2CYP19A1 | |
| SCHEMBL28387649 | 0.82 | HSP90AA1 (0.47) | HSP90AA1 | |
| Hydrochloric Acid SCHEMBL4760945 | 0.82 | HSP90AA1 (0.47) | HSP90AA1 | |
| SCHEMBL171853 | 0.82 | HDAC8 (0.47) | HSP90AA1CYP2A6HDAC8CLK4ADRB2 | |
| Pyridine SCHEMBL28889000 | 0.81 | NAPRT (0.53) | HSP90AA1CYP2A6TDP1 | |
| Dipyridyl SCHEMBL29148818 | 0.79 | KDM4E (0.67) | HSP90AA1CYP2A6KDM4ETDP1TP53 | |
| SCHEMBL17144230 | 0.78 | HDAC8 (0.44) | HSP90AA1CYP2A6HDAC8CLK4ADRB2 | |
| Hydrochloric Acid SCHEMBL6534749 | 0.78 | HDAC8 (0.44) | HSP90AA1CYP2A6HDAC8CLK4ADRB2 | |
| SCHEMBL4270187 | 0.78 | HDAC8 (0.44) | HSP90AA1CYP2A6HDAC8CLK4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551116-A | Structure, preparation and magnetism of trinuclear dysprosium complex based on 2,4, 6-tri (2-pyrimidinyl) -1,3, 5-triazine | 桂林理工大学 | 2024-02-13 | — | — | CN | claimed |
| CN-117551116-A | Structure, preparation and magnetism of trinuclear dysprosium complex based on 2,4, 6-tri (2-pyrimidinyl) -1,3, 5-triazine | 桂林理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117551116-A | Structure, preparation and magnetism of trinuclear dysprosium complex based on 2,4, 6-tri (2-pyrimidinyl) -1,3, 5-triazine | 桂林理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117551116-A | Structure, preparation and magnetism of trinuclear dysprosium complex based on 2,4, 6-tri (2-pyrimidinyl) -1,3, 5-triazine | 桂林理工大学 | 2024-02-13 | — | — | CN | disclosed |
| US-20240026218-A1 | METAL-ASSISTED DELAYED FLUORESCENT MATERIALS AS CO-HOST MATERIALS FOR FLUORESCENT OLEDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2024-01-25 | — | — | US | disclosed |
| US-20240026218-A1 | METAL-ASSISTED DELAYED FLUORESCENT MATERIALS AS CO-HOST MATERIALS FOR FLUORESCENT OLEDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2024-01-25 | — | — | US | disclosed |
| US-11795387-B2 | Metal-assisted delayed fluorescent materials as co-host materials for fluorescent OLEDs | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-11795387-B2 | Metal-assisted delayed fluorescent materials as co-host materials for fluorescent OLEDs | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-20230263002-A1 | ORGANIC LIGHT-EMITTING DIODES WITH FLUORESCENT AND PHOSPHORESCENT EMITTERS | UNIV ARIZONA STATE (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230263002-A1 | ORGANIC LIGHT-EMITTING DIODES WITH FLUORESCENT AND PHOSPHORESCENT EMITTERS | UNIV ARIZONA STATE (US) | 2023-08-17 | — | — | US | disclosed |
| US-20070213325-A1 | Multi-cyclic compound and method of use | AMGEN INC. (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2007100646-A1 | MULTI-CYCLIC COMPOUNDS AND METHOD OF USE | AMGEN INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20070185111-A1 | Aurora kinase modulators and method of use | AMGEN INC. | 2007-08-09 | — | — | US | disclosed |
| EP-1090000-A4 | NAPHTHO 1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1089729-A4 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001029045-A1 | GRAM-POSITIVE SELECTIVE ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2001-04-26 | — | — | WO | disclosed |
| EP-1090000-A1 | NAPHTHO 1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1089729-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999066927-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999067242-A1 | NAPHTHO[1,8-DE]THIASIN-2-YL METHYL CARBAPENEM ANTIBACTERIALS | MERCK & CO., INC. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185111-A1 | Aurora kinase modulators and method of use | AURKC, AURKA, CDK1 | HSP90AA1 2278/4885CYP2A6 2733/4885HDAC8 1199/4885 |
| US-20070213325-A1 | Multi-cyclic compound and method of use | TIE1, CDK1, CCNB1 | HSP90AA1 3306/4885CYP2A6 3190/4885HDAC8 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.