SCHEMBL5864535

SCHEMBL5864535

CC(C)(Cl)c1nc(N)nc(Cl)n1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20502388 0.84 HRH4 (0.43) HSP90AA1LMNASMN1; SMN2HRH4ALDH1A1
SCHEMBL5864462 0.80 HSP90AA1 (0.33) HSP90AA1LMNASMN1; SMN2HRH4ALOX15
SCHEMBL27181360 0.80 HSP90AA1 (0.33) HSP90AA1LMNASMN1; SMN2HRH4ALOX15
SCHEMBL21834206 0.77 HSD17B10 (0.43) HSP90AA1
SCHEMBL27692749 0.77 ADORA2A (0.32) HSP90AA1
SCHEMBL5864479 0.74 TSHR (0.42) HSP90AA1LMNASMN1; SMN2ALDH1A1ALOX15
SCHEMBL5864575 0.72 HSP90AB1 (0.50) HSP90AA1
SCHEMBL197055 0.71
SCHEMBL79810 0.71
SCHEMBL11568870 0.70 TSHR (0.38) HSP90AA1LMNASMN1; SMN2ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7002011-B1 Process for the preparation of 2-amino-4-chloro-1,3,5-triazines AVENTIS CROPSCIENCE GMBH (DE) 2006-02-21 US disclosed
CN-1155582-C Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines �Ϻ���ͨ��ѧ 2004-06-30 CN disclosed
CN-1306518-A Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines AVENTIES CROPS SCIENCES GMBH (DE) 2001-08-01 CN disclosed
EP-1097146-A1 METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES Aventis CropScience GmbH (DE) 2001-05-09 EP disclosed
WO-2000002868-A1 METHOD FOR PRODUCING 2-AMINO-4-CHLORO-1, 3, 5-TRIAZINES AVENTIS CROPSCIENCE GMBH (DE) 2000-01-20 WO disclosed