Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.71 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865668 | 1.00 | AR (0.71) | ARHTR6HTTMEN1KMT2A | |
| SCHEMBL4040774 | 1.00 | AR (0.71) | ARHTR6HTTMEN1KMT2A | |
| SCHEMBL4040772 | 1.00 | AR (0.71) | ARHTR6HTTMEN1KMT2A | |
| SCHEMBL7211132 | 1.00 | AR (0.71) | ARHTR6HTTMEN1KMT2A | |
| SCHEMBL5865677 | 0.85 | AR (0.71) | AR | |
| SCHEMBL5865675 | 0.85 | AR (0.71) | AR | |
| SCHEMBL6211148 | 0.85 | AR (0.71) | AR | |
| SCHEMBL5865672 | 0.85 | AR (0.71) | AR | |
| SCHEMBL13964673 | 0.85 | AR (0.71) | AR | |
| SCHEMBL13964575 | 0.85 | AR (0.71) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001911-B2 | Fused cyclic modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-21 | — | — | US | claimed |
| US-7001911-B2 | Fused cyclic modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-21 | — | — | US | disclosed |