Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5980727 | 0.99 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL29350743 | 0.99 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL39146 | 0.99 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL11457333 | 0.97 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL27600005 | 0.97 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBKDM4E | |
| Phenol SCHEMBL28007822 | 0.94 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBKDM4E | |
| Toluene SCHEMBL29114791 | 0.93 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL11907376 | 0.91 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL4896803 | 0.90 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL10154219 | 0.89 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274341-B1 | METHODS FOR PREPARING CATALYST SYSTEMS | UNIVATION TECH LLC (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20110034324-A1 | Methods for Preparing Catalyst Systems | UNIVATION TECHNOLOGIES, LLC (US) | 2011-02-10 | — | — | US | disclosed |
| US-20040254312-A1 | Polymerization process | MAWSON SIMON (US) | 2004-12-16 | — | — | US | disclosed |
| US-20040162402-A1 | Polymerization process | MAWSON SIMON (US) | 2004-08-19 | — | — | US | disclosed |
| CN-1481280-A | Method for supporting catalyst and polymerization using supported catalyst | �������ٶ������������ι�˾ | 2004-03-10 | — | — | CN | disclosed |
| US-20030171513-A1 | Polymerization process | MAWSON SIMON (US) | 2003-09-11 | — | — | US | disclosed |
| US-20030008980-A1 | Continuously combining a catalyst slurry with a catalyst solution to form a catalyst formulation; combining the catalyst with olefin(s) in a polymerization reactor to form a polymer product; measuring sample of polymer; changing | UNIVATION TECHNOLOGIES, LLC | 2003-01-09 | — | — | US | disclosed |
| US-20020107342-A1 | Combines a catalyst component containing slurry and a catalyst component containing solution to form the completed catalyst composition for introduction into the polymerization reactor; polymerizing olefins | UNIVATION TECHNOLOGIES, LLC | 2002-08-08 | — | — | US | disclosed |