SCHEMBL5865802

SCHEMBL5865802

[CH2]CO/C=C/C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294463 1.00
SCHEMBL294462 1.00
SCHEMBL293646 0.81
SCHEMBL293647 0.81
SCHEMBL437922 0.75
SCHEMBL294782 0.75
SCHEMBL294783 0.75
SCHEMBL14197614 0.72
SCHEMBL6722145 0.72
SCHEMBL1475674 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7087272-B2 negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements MERCK PATENT GMBH (DE) 2006-08-08 US disclosed
US-7029730-B2 components of liquid-crystalline media, in particular for displays based on the twisted cell principle, the guest-host effect, the deformation of aligned phases, electrically controlled birefringence, color super homeotropic, vertically aligned or in plane switching effect or dynamic scattering effect MERCK PATENT GMBH (DE) 2006-04-18 US disclosed
US-6916513-B2 High dielectric anisotropy and low birefringence; liquid crystal mixtures MERCK PATENT GMBH (DE) 2005-07-12 US disclosed
US-6875894-B2 Electrophilic activity; fluorination, alkylation to nucleophilic compounds MERCK PATENT GMBH (DE) 2005-04-05 US disclosed
US-20040167361-A1 Compounds of liquid crystal structure for optical devices MERCK PATENT GMBH (DE) 2004-08-26 US disclosed
US-20040106798-A1 negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements MERCK PATENT GMBH (DE) 2004-06-03 US disclosed
US-20040063985-A1 Bis(alkylthio)carbenium salts MERCK PATENT GMBH (DE) 2004-04-01 US disclosed
EP-1373434-A1 FLUORINATED FLUORENE DERIVATIVES MERCK PATENT GmbH (DE) 2004-01-02 EP disclosed
EP-1373175-A2 2,4'-SUBSTITUTED 6-CYCLOHEXYL-TRANS-DECALINES MERCK PATENT GmbH (DE) 2004-01-02 EP disclosed
WO-2002098832-A1 CF2O-BRIDGED, AXIALLY SUBSTITUTED CYCLOHEXANE DERIVATIVES. MERCK PATENT GMBH (DE) 2002-12-12 WO disclosed
WO-2002081418-A2 2,4'-SUBSTITUTED 6-CYCLOHEXYL-TRANS-DECALINES MERCK PATENT GMBH (DE) 2002-10-17 WO disclosed
WO-2002079344-A1 FLUORINATED FLUORENE DERIVATIVES MERCK PATENT GMBH (DE) 2002-10-10 WO disclosed
WO-2002064583-A2 BIS(ALKYLTHIO)CARBENIUM SALTS MERCK PATENT GMBH (DE) 2002-08-22 WO disclosed