Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 2/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5702675 | 0.98 | S1PR2 (0.58) | S1PR2S1PR1PPARGPPARACYP2C9 | |
| Bromide SCHEMBL5702706 | 0.98 | S1PR2 (0.58) | S1PR2S1PR1PPARGPPARACYP2C9 | |
| SCHEMBL6467442 | 0.90 | S1PR2 (0.63) | S1PR2S1PR1PPARGPPARACYP2C9 | |
| SCHEMBL27453353 | 0.85 | S1PR2 (0.60) | S1PR2S1PR1LMNAS1PR3HDAC3 | |
| SCHEMBL1669596 | 0.85 | S1PR2 (0.60) | S1PR2S1PR1LMNAS1PR3HDAC3 | |
| SCHEMBL4991043 | 0.82 | S1PR2 (0.48) | S1PR2S1PR1PPARGPPARACYP2C9 | |
| SCHEMBL6049800 | 0.80 | S1PR2 (0.63) | S1PR2S1PR1KMT2AS1PR3HDAC3 | |
| SCHEMBL5079189 | 0.80 | PPARA (0.59) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL5079192 | 0.80 | PPARA (0.59) | PPARGPPARAHDAC3HDAC4HDAC1 | |
| SCHEMBL4990585 | 0.80 | S1PR2 (0.49) | S1PR2S1PR1PPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045653-B2 | cyclopentyl substituted glutaramide derivatives; inhibitors of neutral endopeptidase which may be used to treat cardiovascular disorders, especially hypertension | PFIZER, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20050075392-A1 | Novel pharmaceuticals | DACK KEVIN NEIL (GB) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075392-A1 | Novel pharmaceuticals | MME, ECE1, ECE2 | S1PR2 1206/4885S1PR1 761/4885PPARG 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.