Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.85 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.75 |
| ▸ | FLT1 | P17948 | 10/20 | 0.75 |
| ▸ | KDR | P35968 | 1/20 | 0.75 |
| ▸ | BCR | P11274 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533317 | 0.99 | ABL1 (0.87) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3535477 | 0.93 | ABL1 (0.74) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3543331 | 0.93 | ABL1 (0.74) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3535571 | 0.93 | ABL1 (0.98) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL5866633 | 0.93 | ABL1 (0.77) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3534492 | 0.92 | ABL1 (0.75) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3533705 | 0.92 | ABL1 (1.00) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3538577 | 0.90 | ABL1 (0.80) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3540415 | 0.90 | FGFR1 (0.73) | ABL1FGFR1FLT1KDRBCR | |
| SCHEMBL3537624 | 0.88 | ABL1 (0.82) | ABL1FGFR1FLT1KDRBCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |