Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.57 |
| ▸ | FLT1 | P17948 | 7/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866698 | 1.00 | FGFR1 (0.57) | FGFR1FLT1ABL1PDPK1ACHE | |
| SCHEMBL5866750 | 0.90 | FGFR1 (0.71) | FGFR1FLT1ABL1PDPK1KDR | |
| SCHEMBL3537272 | 0.90 | FGFR1 (0.71) | FGFR1FLT1ABL1PDPK1KDR | |
| SCHEMBL3540367 | 0.87 | FGFR1 (0.60) | FGFR1FLT1ABL1PDPK1ACHE | |
| SCHEMBL3538980 | 0.83 | FGFR1 (0.64) | FGFR1FLT1ABL1PDPK1ACHE | |
| SCHEMBL3537572 | 0.83 | FGFR1 (0.64) | FGFR1FLT1ABL1ACHEKDR | |
| SCHEMBL3543818 | 0.82 | FGFR1 (0.53) | FGFR1FLT1ABL1PDPK1ACHE | |
| SCHEMBL3536846 | 0.81 | FGFR1 (0.47) | FGFR1FLT1ABL1PDPK1ACHE | |
| SCHEMBL3543030 | 0.78 | FGFR1 (0.63) | FGFR1FLT1PDPK1KDRFGFR3 | |
| SCHEMBL5866656 | 0.78 | FGFR1 (0.52) | FGFR1FLT1ABL1PDPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |