Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 13/20 | 0.39 |
| ▸ | FLT1 | P17948 | 11/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536592 | 0.89 | FGFR1 (0.40) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL5866691 | 0.88 | FGFR1 (0.40) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3538199 | 0.87 | FGFR1 (0.42) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3532400 | 0.87 | FGFR1 (0.54) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3538875 | 0.86 | PDPK1 (0.49) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3534989 | 0.86 | FGFR1 (0.38) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL5866702 | 0.85 | CHEK1 (0.44) | FGFR1FLT1PDPK1ABL1FLT3 | |
| SCHEMBL3536775 | 0.85 | FGFR1 (0.45) | FGFR1FLT1PDPK1ABL1BCR | |
| SCHEMBL3540634 | 0.84 | PDPK1 (0.34) | FGFR1FLT1PDPK1FLT3KDR | |
| SCHEMBL3534254 | 0.84 | FGFR1 (0.43) | FGFR1FLT1PDPK1ABL1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | disclosed |