Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 15/20 | 0.87 |
| ▸ | ACE | P12821 | 12/20 | 0.81 |
| ▸ | CPA1 | P15085 | 12/20 | 0.81 |
| ▸ | ACE2 | Q9BYF1 | 12/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255029 | 1.00 | MME (0.87) | MMEACECPA1ACE2 | |
| SCHEMBL5869120 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL5869122 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL5869127 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL5869124 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL5870542 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL9068713 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8005905 | 0.87 | MME (0.87) | MMEACECPA1ACE2 | |
| SCHEMBL8861742 | 0.85 | MME (0.88) | MMEACECPA1ACE2 | |
| SCHEMBL8861738 | 0.85 | MME (0.88) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045532-B2 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | disclosed |