Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 13/20 | 0.56 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586956 | 1.00 | PLG (0.56) | PLGCHIT1CHIAGABRA1GABRG2 | |
| SCHEMBL586955 | 1.00 | PLG (0.56) | PLGCHIT1CHIAGABRA1GABRG2 | |
| SCHEMBL581453 | 0.92 | PLG (0.42) | PLGCHIT1CHIAENPP2TACR1 | |
| SCHEMBL3074964 | 0.92 | PLG (0.42) | PLGCHIT1CHIAENPP2TACR1 | |
| SCHEMBL587117 | 0.92 | PLG (0.42) | PLGCHIT1CHIAENPP2TACR1 | |
| SCHEMBL3073252 | 0.92 | PLG (0.42) | PLGCHIT1CHIAENPP2TACR1 | |
| SCHEMBL587340 | 0.88 | PLG (0.54) | PLG | |
| SCHEMBL587197 | 0.86 | PLG (0.50) | PLGGABRA1GABRG2GABRB3 | |
| SCHEMBL581961 | 0.85 | PLG (0.53) | PLGGABRA1GABRG2GABRB3TACR1 | |
| SCHEMBL581507 | 0.83 | PLG (0.54) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417131-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |