Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31622797 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622786 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622783 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622800 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622801 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL5871868 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL6656457 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622794 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL6658710 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 | |
| SCHEMBL31622795 | 0.98 | TSHR (0.74) | TSHRRAD52NPSR1NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231288-A1 | IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2021-11-18 | — | — | WO | claimed |
| WO-2021162938-A1 | COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM | SIRRUS, INC. (US) | 2021-08-19 | — | — | WO | claimed |
| EP-3789408-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2021-03-10 | — | — | EP | claimed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| EP-3191530-B1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-11-11 | — | — | EP | claimed |
| CN-111825785-A | Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds | 赛鲁斯股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-107075223-B | Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds | 赛鲁斯股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| EP-3683267-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2020-07-22 | — | — | EP | claimed |
| EP-3191546-B1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-07-22 | — | — | EP | claimed |
| US-10633566-B2 | Polymers containing a 1,1-disubstituted alkene compound | SIRRUS, INC. (US) | 2020-04-28 | — | — | US | claimed |
| EP-3191546-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | claimed |
| US-20170198181-A1 | EMULSION INCLUDING POLYMERS CONTAINING A 1,1-DISUBSTITUTED ALKENE COMPOUND, ADHESIVES, COATINGS, AND METHODS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-07-13 | — | — | US | claimed |
| US-20170190807-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2017-07-06 | — | — | US | claimed |
| US-9676875-B2 | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions | SIRRUS, INC. (US) | 2017-06-13 | — | — | US | claimed |
| US-9637564-B2 | Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions | SIRRUS, INC. (US) | 2017-05-02 | — | — | US | claimed |
| US-20160096906-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-04-07 | — | — | US | claimed |
| US-20160096907-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-04-07 | — | — | US | claimed |
| WO-2016040012-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| US-20160068616-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-03-10 | — | — | US | claimed |
| US-9279022-B1 | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions | SIRRUS, INC. (US) | 2016-03-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633566-B2 | Polymers containing a 1,1-disubstituted alkene compound | ALG8, PCNA, PARP1 | TSHR 4710/4885RAD52 229/4885NPSR1 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.