Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.56 |
| ▸ | FAP | Q12884 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5871430 | 0.94 | DPP4 (0.61) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5075942 | 0.94 | DPP7 (0.69) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5075940 | 0.94 | DPP7 (0.69) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8274082 | 0.86 | DPP4 (0.66) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2860107 | 0.84 | DPP7 (0.84) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2860101 | 0.84 | DPP7 (0.84) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5871933 | 0.82 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL160102 | 0.79 | DPP4 (1.00) | DPP4DPP7DPP8 | |
| SCHEMBL29416829 | 0.79 | DPP4 (1.00) | DPP4DPP7DPP8 | |
| SCHEMBL220478 | 0.79 | DPP4 (1.00) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125863-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2006-10-24 | — | — | US | claimed |
| EP-1280797-B1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2004-10-13 | — | — | EP | claimed |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2004-04-29 | — | — | US | claimed |
| US-7125863-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2006-10-24 | — | — | US | disclosed |
| EP-1280797-B1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2004-10-13 | — | — | EP | disclosed |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | DPP4, DPP7, DPP3 | DPP4 1/4885DPP7 2/4885DPP8 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.