Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974541 | 0.97 | CA1 (0.55) | CA1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL12722976 | 0.91 | PHF8 (0.48) | CA1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL110531 | 0.85 | CA1 (0.60) | CA1TRPA1ALDH1A1GABRPGABRD | |
| SCHEMBL2213202 | 0.84 | CA1 (0.48) | CA1CYP2D6CYP2C19KDM4CKDM4A | |
| SCHEMBL11051339 | 0.84 | PHF8 (0.52) | CA1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL14350722 | 0.82 | CA1 (0.57) | CA1TRPA1P2RX7ALDH1A1GABRP | |
| SCHEMBL29894122 | 0.80 | CA1 (0.62) | CA1TRPA1P2RX7 | |
| SCHEMBL3959521 | 0.80 | TSHR (0.46) | CA1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL108580 | 0.78 | — | — | |
| SCHEMBL2527424 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6991744-B2 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-01-31 | — | — | US | disclosed |
| US-6962665-B2 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-11-08 | — | — | US | disclosed |
| US-20040222402-A1 | Refrigerant compositions containing a compatibilizer | MINOR BARBARA HAVILAND (US) | 2004-11-11 | — | — | US | disclosed |
| EP-1451263-A1 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEREOF IN A COMPRESSION REFRIGERATION APPARATUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2002046328-A9 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER | DU PONT (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20030209688-A1 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-13 | — | — | US | disclosed |
| EP-1341868-A2 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2003050200-A1 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER AND USE THEROF IN A COMPRESSION REFRIGERATION APPARATUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
| US-20030034477-A1 | Refrigerant compositions containing a compatibilizer | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-02-20 | — | — | US | disclosed |
| WO-2002046328-A2 | REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |