SCHEMBL5872528

SCHEMBL5872528

Fc1c(F)c(F)c2c(c1F)C(F)c1c(F)c(F)c(F)c(F)c1C2F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
USP2 O75604 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6427743 0.96 KDM1A (0.36) KDM1AMAOAMAOB
SCHEMBL890426 0.85 KDM1A (0.35) KDM1AMAOAMAOB
SCHEMBL23190508 0.69 KDM1A (0.35) KDM1AMAOAMAOB
SCHEMBL24425425 0.69 KDM1A (0.35) KDM1AMAOAMAOB
SCHEMBL24425422 0.67 KDM1A (0.33) KDM1AMAOAMAOB
SCHEMBL23190379 0.67 KDM1A (0.33) KDM1AMAOAMAOB
SCHEMBL42968 0.65 GRIN2D (0.33)
SCHEMBL18020965 0.62 KDM1A (0.35) KDM1AMAOAMAOB
SCHEMBL245064 0.61
SCHEMBL2252341 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425318-B1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS VERSALIS SPA (IT) 2013-01-16 EP disclosed
US-7081505-B2 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2006-07-25 US disclosed
US-20040198934-A1 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2004-10-07 US disclosed
EP-1425318-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS Polimeri Europa S.p.A. (IT) 2004-06-09 EP disclosed
WO-2003010210-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS POLIMERI EUROPA S.P.A. (IT) 2003-02-06 WO disclosed