Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412811 | 0.84 | TSHR (0.66) | TSHRTP53ALDH1A1LMNAMAPT | |
| SCHEMBL225582 | 0.84 | TSHR (0.66) | TSHRTP53ALDH1A1LMNAMAPT | |
| SCHEMBL3642689 | 0.83 | TP53 (0.59) | TSHRTP53L3MBTL1ACACBALDH1A1 | |
| SCHEMBL227153 | 0.83 | TP53 (0.63) | TSHRTP53ACACBMAPTHPGD | |
| SCHEMBL31412800 | 0.83 | TP53 (0.63) | TSHRTP53ACACBMAPTHPGD | |
| SCHEMBL204959 | 0.81 | TP53 (0.61) | TSHRTP53LMNAHPGDTAAR1 | |
| SCHEMBL1148 | 0.81 | TSHR (0.61) | TSHRTP53L3MBTL1ACACBALDH1A1 | |
| SCHEMBL13889195 | 0.81 | TP53 (0.61) | TSHRTP53MAPTSMN1; SMN2TAAR1 | |
| SCHEMBL21439149 | 0.81 | TP53 (0.61) | TSHRTP53LMNAHPGDTAAR1 | |
| SCHEMBL17550074 | 0.81 | TSHR (0.61) | TSHRTP53TDP1ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132000-B2 | Agents for oxidatively dying keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | claimed |
| EP-1499281-A1 | AGENTS FOR OXIDATIVELY DYING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-26 | — | — | EP | claimed |
| US-20040187226-A1 | Agents for oxidatively dying keratin fibers | Wella GmbH (DE) | 2004-09-30 | — | — | US | claimed |
| WO-2003090700-A1 | AGENTS FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | WO | claimed |
| US-7132000-B2 | Agents for oxidatively dying keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | disclosed |
| EP-1499281-A1 | AGENTS FOR OXIDATIVELY DYING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-20040187226-A1 | Agents for oxidatively dying keratin fibers | Wella GmbH (DE) | 2004-09-30 | — | — | US | disclosed |
| WO-2003090700-A1 | AGENTS FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040187226-A1 | Agents for oxidatively dying keratin fibers | KRT18, GPX1, CBR1 | TSHR 4630/4885TP53 1449/4885MAPK1 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.