Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994919 | 0.85 | HSD17B10 (0.52) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL489823 | 0.81 | HSD17B10 (0.57) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL12361317 | 0.80 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7129588 | 0.79 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7122088 | 0.79 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7122083 | 0.79 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL3723517 | 0.79 | POLB (0.51) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL10031609 | 0.79 | HSD17B10 (0.57) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL903389 | 0.79 | HSD17B10 (0.57) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL15924964 | 0.78 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045360-B2 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020090728-A1 | Method for analysis of reaction products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-07-11 | — | — | US | disclosed |
| WO-2001057526-A1 | METHOD FOR ANALYSIS OF REACTION PRODUCTS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-08-09 | — | — | WO | disclosed |