Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.31 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.31 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.31 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873802 | 1.00 | MAP3K11 (0.31) | MAP3K11TLK2NEK7NEK6 | |
| SCHEMBL5425570 | 0.84 | MAP3K11 (0.44) | MAP3K11TLK2NEK7NEK6 | |
| SCHEMBL5894604 | 0.84 | MAP3K11 (0.44) | MAP3K11TLK2NEK7NEK6 | |
| SCHEMBL5425576 | 0.84 | MAP3K11 (0.44) | MAP3K11TLK2NEK7NEK6 | |
| SCHEMBL5430107 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL5430111 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL5873955 | 0.66 | KMT2A (0.39) | — | |
| SCHEMBL6872495 | 0.66 | KMT2A (0.39) | — | |
| SCHEMBL5432278 | 0.64 | MAP3K11 (0.46) | MAP3K11TLK2NEK7NEK6 | |
| SCHEMBL5873872 | 0.64 | MAP3K11 (0.46) | MAP3K11TLK2NEK7NEK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129253-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |