Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.75 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917112 | 0.89 | AR (0.79) | ARSRD5A1SRD5A2 | |
| SCHEMBL7239501 | 0.88 | AR (0.78) | ARSRD5A1SRD5A2 | |
| SCHEMBL14504019 | 0.88 | AR (0.78) | ARSRD5A1SRD5A2 | |
| SCHEMBL7080268 | 0.88 | AR (0.78) | ARSRD5A1SRD5A2 | |
| SCHEMBL915861 | 0.88 | AR (0.80) | ARSRD5A1SRD5A2 | |
| SCHEMBL917166 | 0.88 | AR (0.78) | ARSRD5A1SRD5A2 | |
| SCHEMBL5215286 | 0.88 | AR (0.80) | ARSRD5A1SRD5A2 | |
| SCHEMBL5219959 | 0.87 | AR (0.75) | ARSRD5A1SRD5A2 | |
| SCHEMBL917806 | 0.87 | AR (0.75) | ARSRD5A1SRD5A2 | |
| SCHEMBL5214319 | 0.86 | AR (0.65) | ARSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859761-A4 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | MERCK & CO INC (US) | 2000-01-26 | — | — | EP | claimed |
| EP-0859761-A1 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | Merck & Co., Inc. (US) | 1998-08-26 | — | — | EP | claimed |
| WO-1997010217-A1 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | MERCK & CO., INC. (US) | 1997-03-20 | — | — | WO | claimed |
| US-RE39056-E1 | 4-Azasteroids for treatment of hyperandrogenic conditions | MERCK & CO, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| EP-0859761-A4 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | MERCK & CO INC (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6001844-A | 4-Azasteroids for treatment of hyperandrogenic conditions | MERCK & CO., INC. (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0859761-A1 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | Merck & Co., Inc. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997010217-A1 | 4-AZASTEROIDS FOR TREATMENT OF HYPERANDROGENIC CONDITIONS | MERCK & CO., INC. (US) | 1997-03-20 | — | — | WO | disclosed |