⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20440144 | 1.00 | — | — | |
| SCHEMBL27947942 | 0.79 | — | — | |
| SCHEMBL30508151 | 0.76 | — | — | |
| SCHEMBL1031550 | 0.76 | — | — | |
| SCHEMBL3283687 | 0.73 | — | — | |
| SCHEMBL28758607 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL27553220 | 0.71 | — | — | |
| SCHEMBL2995714 | 0.71 | — | — | |
| SCHEMBL21417686 | 0.71 | — | — | |
| SCHEMBL6973206 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192673-A1 | Compounds | STEP PHARMA S.A.S. (FR) | 2023-06-22 | — | — | US | disclosed |
| US-20230086703-A1 | N-(4-(5-chloropyridin-3-yl)phenyl)-2-(2-(cyclopropanesulfonamido)pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | STEP PHARMA S.A.S. (FR) | 2023-03-23 | — | — | US | disclosed |
| WO-2021237121-A1 | SUBSTITUTED PYRIDINES | GOSSAMER BIO SERVICES, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2020115190-A1 | NOVEL ANTIBACTERIAL 3\"-DERIVATIVES OF 4,6-DISUBSTITUTED 2,5-DIDEOXYSTREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS | AGILEBIOTICS B.V. (NL) | 2020-06-11 | — | — | WO | disclosed |
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-105828610-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-104603113-A | Novel 2, 3-dihydro-1H-imidazo {1,2-a } pyrimidin-5-one and 1,2,3, 4-tetrahydropyrimidino {1,2-a } pyrimidin-6-one derivatives comprising substituted morpholines, preparation thereof and pharmaceutical use thereof | SANOFI SA | 2015-05-06 | — | — | CN | disclosed |
| EP-2416765-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC Therapeutics, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117939-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |