Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminobenzoic Acid SCHEMBL8846510 | 0.91 | TSHR (0.57) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL369042 | 0.91 | TSHR (0.57) | TSHRTP53SRD5A2KDM4EMAPT | |
| Terephthalic Acid SCHEMBL27934768 | 0.91 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL8745085 | 0.87 | TSHR (0.52) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL1111501 | 0.87 | TSHR (0.52) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL301626 | 0.87 | TSHR (0.52) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL1252611 | 0.87 | TSHR (0.52) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL8249 | 0.86 | TSHR (0.71) | TSHRTP53SRD5A2KDM4EMAPT | |
| Terephthalic Acid SCHEMBL7648718 | 0.86 | TSHR (0.71) | TSHRTP53SRD5A2KDM4EMAPT | |
| Aminobenzoic Acid SCHEMBL1768920 | 0.86 | TSHR (0.71) | TSHRTP53SRD5A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |