Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688464 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20711188 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28110318 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11350827 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25521022 | 0.98 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| Water SCHEMBL7553028 | 0.98 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25475053 | 0.96 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2419509 | 0.96 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14747967 | 0.95 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29744995 | 0.93 | NR1I2 (0.42) | CYSLTR2CYSLTR1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018966-B2 | Compositions and methods for preventing gel formation comprising a siloxane and an alkylamine | GENERAL ELECTRIC COMPANY (US) | 2006-03-28 | — | — | US | disclosed |