Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27902474 | 1.00 | FFAR3 (0.58) | FFAR3LCKFYNTP53LMNA | |
| Acetic Acid SCHEMBL574619 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNTP53LMNA | |
| Acetic Acid SCHEMBL28843588 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNTP53LMNA | |
| Acetic Acid SCHEMBL9659096 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNTP53LMNA | |
| Acetic Acid SCHEMBL174567 | 0.96 | — | — | |
| Acetic Acid SCHEMBL1679496 | 0.92 | — | — | |
| Acetic Acid SCHEMBL3042211 | 0.92 | — | — | |
| Acetic Acid SCHEMBL27861658 | 0.92 | FFAR3 (0.58) | FFAR3LCKFYNTP53LMNA | |
| Acetic Acid SCHEMBL16563111 | 0.92 | — | — | |
| Acetic Acid SCHEMBL27649055 | 0.92 | FFAR3 (0.58) | FFAR3LCKFYNTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071371-B2 | Gel catalysts and methods for their use in catalytic dehydrogenation processes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| US-20040116760-A1 | Gel catalysts and methods for their use in catalytic dehydrogenation processes | KOURTAKIS KOSTANTINOS (US) | 2004-06-17 | — | — | US | disclosed |
| US-6696388-B2 | FOR DEHYDROGENATION OF PARAFFINS TO OLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-02-24 | — | — | US | disclosed |
| US-20030023126-A1 | Gel catalysts and methods for their use in catalytic dehydrogenation processes | E.I. DU PONT DE NEMOURS AND COMPANY | 2003-01-30 | — | — | US | disclosed |
| EP-1250191-A2 | GEL CATALYSTS AND METHODS FOR THEIR USE IN CATALYTIC DEHYDROGENATION PROCESSES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001052985-A2 | GEL CATALYSTS AND METHODS FOR THEIR USE IN CATALYTIC DEHYDROGENATION PROCESSES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |