Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508420 | 0.88 | CYP1A2 (0.42) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL14570727 | 0.86 | CYP1A2 (0.41) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL1547491 | 0.85 | KDM4E (0.47) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL13023338 | 0.84 | CYP1A2 (0.42) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL4612461 | 0.82 | ESR1 (0.59) | CYP2D6ESR1CYP19A1CYP11B2KMT2A | |
| SCHEMBL4612464 | 0.82 | ESR1 (0.59) | CYP2D6ESR1CYP19A1CYP11B2KMT2A | |
| SCHEMBL9806354 | 0.81 | NR4A1 (0.52) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL9806349 | 0.81 | NR4A1 (0.52) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL2506548 | 0.80 | NR4A1 (0.43) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 | |
| SCHEMBL2506549 | 0.80 | NR4A1 (0.43) | NR4A1NR4A2NR4A3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478640-A | Method of preparing polysubstituted olefin compound with fluorinated alkene | UNIV EAST CHINA SCIENCE & TECH | 2015-04-01 | — | — | CN | disclosed |
| US-7022867-B2 | Silicon compound and method for making the same | CANON KABUSHIKI KAISHA (JP) | 2006-04-04 | — | — | US | disclosed |
| US-6706839-B1 | COVALENTLY BONDING SEPARATING AGENT TO REACTANT; ISOMERIZATION | UNIVERSITY OF PITTSBURGH | 2004-03-16 | — | — | US | disclosed |
| US-20030216591-A1 | Silicon compound and method for making the same | UENO KAZUNORI (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1165222-A4 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIV PITTSBURGH (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6534198-B1 | Polysilane silicon compound having excellent charge transport characteristics and durability | CANON KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0879841-B1 | Silicon compound, method for making the same, and electroluminescent device using the same | CANON KK (JP) | 2002-10-30 | — | — | EP | disclosed |
| WO-2002066451-A3 | 1,2-DIPHENYL-1-NAPHTHYL ETHENE DERIVATIVES, ANALOGS AND USE THEREOF | NANODESIGN INC (CA) | 2002-10-24 | — | — | WO | disclosed |
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | NANODESIGN INC. (CA) | 2002-10-10 | — | — | US | disclosed |
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | NANODESIGN INC. (CA) | 2002-10-10 | — | — | US | disclosed |
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | NANODESIGN INC. (CA) | 2002-10-10 | — | — | US | disclosed |
| WO-2002066451-A2 | 1,2-DIPHENYL-1-NAPHTHYL ETHENE DERIVATIVES, ANALOGS AND USE THEREOF | NANODESIGN INC. (CA) | 2002-08-29 | — | — | WO | disclosed |
| EP-1165222-A1 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIVERSITY OF PITTSBURGH (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000047031-A2 | CHEMICAL PARTITIONING AGENTS AND METHODS OF USING SAME | UNIVERSITY OF PITTSBURGH (US) | 2000-08-17 | — | — | WO | disclosed |
| EP-0879841-A2 | Silicon compound, method for making the same, and electroluminescent device using the same | CANON KABUSHIKI KAISHA (JP) | 1998-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216591-A1 | Silicon compound and method for making the same | AR, NR5A1, SSTR1 | NR4A1 108/4885NR4A2 407/4885NR4A3 744/4885 |
| US-20020147187-A1 | 1,2-diphenyl-1-naphthyl ethene derivatives, analogs and use thereof | ESR2, ECE1, ECE2 | NR4A1 265/4885NR4A2 213/4885NR4A3 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.