⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831952 | 1.00 | MAPT (0.44) | — | |
| SCHEMBL25832548 | 1.00 | MAPT (0.44) | — | |
| SCHEMBL25167631 | 1.00 | MAPT (0.44) | — | |
| SCHEMBL4231703 | 1.00 | MAPT (0.44) | — | |
| SCHEMBL5879269 | 0.97 | — | — | |
| SCHEMBL151387 | 0.90 | — | — | |
| Bromide SCHEMBL28242105 | 0.88 | — | — | |
| SCHEMBL8382273 | 0.83 | MAPT (0.55) | — | |
| SCHEMBL2520528 | 0.83 | MAPT (0.55) | — | |
| SCHEMBL1232553 | 0.83 | MAPT (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132409-B2 | Adenosine derivatives and use thereof | TOA EIYO LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| US-6936596-B2 | Adenosine derivatives and use thereof | TOA EIYO LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| US-20050130930-A1 | Adenosine derivatives and use thereof | TAO EIYO LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1316559-B1 | ADENOSINE DERIVATIVES AND USE THEREOF | TOA EIYO LTD (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20040053881-A1 | Adenosine derivatives and use thereof | TOA EIYO LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1316559-A1 | ADENOSINE DERIVATIVES AND USE THEREOF | TOA EIYO LTD. (JP) | 2003-06-04 | — | — | EP | disclosed |