Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SGK1 | O00141 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880291 | 1.00 | GAA (0.49) | GAAPKMRXFP1LMNAALDH1A1 | |
| SCHEMBL5879663 | 0.92 | SGK1 (0.50) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5879661 | 0.92 | SGK1 (0.50) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5880187 | 0.90 | SGK1 (0.48) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5880190 | 0.90 | SGK1 (0.48) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5879600 | 0.89 | SGK1 (0.52) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5879604 | 0.89 | SGK1 (0.52) | GAALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL5879754 | 0.86 | MAPT (0.58) | GAALMNAALDH1A1MAPTSGK1 | |
| SCHEMBL5879750 | 0.86 | MAPT (0.58) | GAALMNAALDH1A1MAPTSGK1 | |
| SCHEMBL5879716 | 0.85 | MEN1 (0.47) | GAAPKMLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |