Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 13/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850881 | 0.89 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL10598475 | 0.89 | LPAR3 (0.42) | LPAR3LPAR2LPAR1 | |
| SCHEMBL9463317 | 0.89 | LPAR3 (0.69) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL1083222 | 0.85 | LPAR3 (0.65) | LPAR3LPAR2LPAR1CYP3A4LPAR5 | |
| SCHEMBL812186 | 0.85 | TDP1 (0.36) | LPAR3LPAR2LPAR1 | |
| SCHEMBL57561 | 0.82 | — | — | |
| Ethylene Glycol SCHEMBL19617113 | 0.78 | PPARD (0.36) | LPAR3LPAR2LPAR1 | |
| SCHEMBL8022721 | 0.78 | — | — | |
| SCHEMBL13028277 | 0.77 | LPAR3 (0.33) | LPAR3LPAR2LPAR1 | |
| SCHEMBL6851142 | 0.77 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153925-B2 | Condensation polymers from N, N*-disubstituted disulfonamides | PEWS R GARTH | 2006-12-26 | — | — | US | disclosed |
| US-20060128924-A1 | Novel condensation polymers from N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |